Characterization of phytochemical profile of rhizome of artificial cultured Polygonatum sibiricum with multiple rhizome buds

Abstract Rhizome of Polygonatum sibiricum is both a renowned traditional Chinese remedy and commonly consumed delicacy. Due to the escalating demand excessive overexploitation, there has been growing interest in artificial cultivation this plant recent years. To assess therapeutic benefits artificially cultivated P. , it crucial identify classify its phytochemical components, which are primary bioactive compounds found rhizome. In study, profile an rhizomes with multiple rhizome buds (ACM) was characterized by using untargeted UHPLC-Q-Orbitrap-MS based approach. addition, two-wild-types rhizomes, namely wild-type (WTM) single bud (WTS), were used for comparison. A total 183 phytochemicals, including 20 alkaloids, 48 flavonoids, 33 phenolic acids, 82 terpenoids, tentatively identified. Generally, ACM comparable that WTM WTS. specific, most identified alkaloids approximately half not significantly different. Notably, several phytochemicals potent properties, such as epiberberine, laetanine, sinapic acid, curcumenol, present ACM. Additionally, increased abundance geniposide naringenin, have linked cardioprotective effects. These findings provide valuable insights future utilization .